Modern Production of Vaccines

Major: Biotechnology and Bioengineering
Code of subject: 8.162.00.M.26
Credits: 3.00
Department: Technology of Biologically Active Substances, Pharmacy and Biotechnology
Lecturer: Associate Professor Komarovska-Porokhnyavets Olena Zoryanivna
Semester: 4 семестр
Mode of study: денна
Learning outcomes: •Ability to demonstrate in-depth knowledge of the basics of molecular biotechnology and bioengineering. • Search, analyze and critically evaluate information from various sources. • Argue the choice of methods for solving scientific and applied problems, critically evaluate the results and defend the decisions made.
Required prior and related subjects: prerequisites: Planning and organization of research and statistics processing of results; Academic entrepreneurship co-requisites: Immuno- and DNA diagnostics and identification of GMOs; Genetics and selection of microorganisms; Quality assessment of biological products and biological products
Summary of the subject: Basic biotechnology concept of vaccinology. Vaccines. Classification of vaccines. The composition of the vaccines. Anatoxins. Adjuvants: a classification according to origin, physical and chemical properties and characteristics. Bacterial vaccines for prevention of infectious diseases. Technological scheme of production of bacterial vaccines. Viral vaccines for the prevention of infectious diseases. The composition and technology of production of combined vaccines. Peptide and ribosomal vaccines. Scheme of production of ribosomal vaccines. Plant-based vaccines. Industrial production of vaccines. Requirements for vaccines. Quality control of vaccines. Parameters of quality of vaccines.
Assessment methods and criteria: • current control: oral examination, individual written tests (40%) • summary control: examination (exam) written-oral form (60%)
Recommended books: 1. Комісаренко C. Світова коронавірусна криза. – К.: ЛАТ&K, 2020. – 120 с. 2. Ада Г., Рамсей А. Вакцины, вакцинация и иммунный ответ: Пер. С англ. - М.:Медицина, 2002. - 344 с. 3. Биотехнология / под ред. Е.С.Воронова. - С-Пб.: Гиорд, 2008. - 703 с. 4. Review of Current Vaccine Development Strategies to Prevent Coronavirus Disease 2019 (COVID-19) / B.M. Bennet, J. Wolf , R. Laureano, R. S. Sellers // Toxicologic Pathology – 2020. - V.48 (7). – P. 800-809. 5. Developing covid-19 vaccines at pandemic speed / Lurie, N, Saville, M, Hatchett, R, Halton, J. // N Engl J Med. – 2020. - V.382. – P. 1969–1973.