Industrial Microbiology and Sanitation

Major: Industrial Pharmacy
Code of subject: 7.226.02.O.014
Credits: 7.00
Department: Technology of Biologically Active Substances, Pharmacy and Biotechnology
Lecturer: Associate Professor, Ph.D. Veronika Chervetsova
Semester: 2 семестр
Mode of study: денна
Мета вивчення дисципліни: The purpose of studying the discipline is the formation of students' system of knowledge in general and special microbiology, namely the signs and properties of microorganisms; course of basic biochemical processes; ecology and relationships between microorganisms, familiarization with methods of clinical microbiology and diseases caused by bacteria, viruses, protozoa.
Завдання: The study of an educational discipline involves the formation of competencies in students of education: Integral competence (INT): Ability to solve problems of research and / or innovation in the field of industrial production of medicines General competencies: GC02. Knowledge and understanding of the subject area; understanding of professional activities. GC05. Ability to evaluate and ensure the quality of work performed. Professional competencies: PC20. Ability to conduct stability studies of medicines and take measures for the proper storage of medicines in their industrial production.
Learning outcomes: PLO01. To have and apply specialized conceptual knowledge in the field of pharmacy and related fields, taking into account modern scientific achievements. PLO02. To critically comprehend scientific and applied problems in the field of pharmacy. PLO03. To have specialized knowledge and skills to solve professional problems and tasks, including for the purpose of further development of knowledge and procedures in the field of pharmacy. PLO04. Communicate fluently in the state and English languages orally and in writing to discuss professional problems and performance, present research and innovative projects. PLO05. Evaluate and ensure the quality and effectiveness of activities in the field of pharmacy. PLO06. To develop and make effective decisions to solve complex / complex problems of pharmacy personally and based on the results of joint discussion; to formulate goals of own and team activities, taking into account social and industrial interests, general strategy and existing constraints, to determine the best ways to achieve goals. PLO08. Develop and implement innovative projects in the field of pharmacy, as well as related interdisciplinary projects, taking into account technical, social, economic, ethical, legal and environmental aspects. PLO10. Ensure the quality of pharmaceutical products, develop integrated quality systems at the pharmaceutical enterprise, taking into account the provisions of international standards, pharmaceutical quality system and good manufacturing practice. PLO15. Investigate the stability of active pharmaceutical ingredients and medicinal products, establish shelf life and storage conditions, ensure proper storage conditions in production.
Required prior and related subjects: Pre-requisites: - Introduction To The Profession And History Of Industrial Pharmacy - Organic Сhemistry Co-requisites: - Physiology With the Basics of Anatomy - Biological Сhemistry and Molecular biology - Quality Control of Medicines - Bioengineering Technologies for the Production of Biologically Active Substances, Biopolymers and Nanostructures - Industrial Biotechnology
Summary of the subject: Morphology and diversity of microorganisms. Cultivation and growth of microorganisms. The influence of environmental factors on microorganisms. The metabolism of microorganisms. Alcohol, lactic and propionic acid fermentation. Respiration (Krebs cycle and respiratory chain). Genetics of microorganisms. Genetic recombination of prokaryotes. Regulation of metabolism in microorganisms. Ecology of microorganisms. Distribution of microorganisms in the air, water and soil. Relationship between microorganisms. Normal microflora of human. Clinical Microbiology. Diseases caused by different types of microorganisms.
Опис: The presentation of the material begins with a short historical essay on the discovery of microorganisms and the development of microbiology. The place of microorganisms in the living system, their structure and chemical composition, nutrition, cultivation methods, and the influence of environmental factors are considered. The diversity of prokaryotic and eukaryotic microorganisms, their modern taxonomy, distribution in nature is presented. Features of energy and constructive exchanges of microorganisms, mechanisms of regulation of these processes, as well as possible ways of using microorganisms and products of their metabolism for practical purposes are highlighted. Considerable attention is paid to the genetics of microorganisms. The material of the last chapters is devoted to the relationship between micro- and macroorganisms, individual pathogenic microorganisms and the infectious diseases they cause are described.
Assessment methods and criteria: Methods used during classes: - lectures are held in the form of conversation, discussion, using diagrams, various handouts and multimedia technologies; - laboratory classes are conducted in the form of performing laboratory works according to the proposed methods; - independent work is carried out in the form of completing individual tasks, their design and protection.
Критерії оцінювання результатів навчання: •Current control – 40 points ( written reports on laboratory work, oral examination – 20 points •Latin names of microorganisms (dictation – 10 points) • Interval control - (10 points) •Final control - (60 points, credit), written form – 50 points, oral component – 10 points
Порядок та критерії виставляння балів та оцінок: 100–88 points – (“excellent”) is awarded for a high level of knowledge (some inaccuracies are allowed) of the educational material of the component contained in the main and additional recommended literary sources, the ability to analyze the phenomena being studied in their interrelationship and development, clearly, succinctly, logically, consistently answer the questions, the ability to apply theoretical provisions when solving practical problems; 87–71 points – (“good”) is awarded for a generally correct understanding of the educational material of the component, including calculations, reasoned answers to the questions posed, which, however, contain certain (insignificant) shortcomings, for the ability to apply theoretical provisions when solving practical tasks; 70 – 50 points – (“satisfactory”) awarded for weak knowledge of the component’s educational material, inaccurate or poorly reasoned answers, with a violation of the sequence of presentation, for weak application of theoretical provisions when solving practical problems; 49-26 points - ("not certified" with the possibility of retaking the semester control) is awarded for ignorance of a significant part of the educational material of the component, significant errors in answering questions, inability to apply theoretical provisions when solving practical problems; 25-00 points - ("unsatisfactory" with mandatory re-study) is awarded for ignorance of a significant part of the educational material of the component, significant errors in answering questions, inability to navigate when solving practical problems, ignorance of the main fundamental provisions.
Recommended books: 1. Mikrobiolohiya: pidruchnyk: [dlya stud.vyshch.navch.zakl.]/ S. P. Hudz, S. O. Hnatush, I. S. Bilinska. – Lviv: Vydavnychyy tsentr LNU imeni Ivana Franka, 2009. – 360 s. 2. Prescott L. M., Harley J. P., Klein D. A. Microbiology, Third Edition. – Dubuque: WCB, 1996. – 936 p. 3. Chervetsova V. H. Mikrobiolohiya: konsp. lektsiy dlya studentiv Instytutu khimiyi ta khimichnykh tekhnolohiy / V.H. Chervetsova. – L?viv: Vydavnytstvo Lvivskoyi politekhniky, 2019. – 180 s. 4. Klymyuk S.I., Sytnyk I.O., Tvorko M.S.. Shyrokobokov V.P. Praktychna mikrobiolohiya: Posibnyk. – Ternopil: Ukrmedknyha. 2004. – 440 s. 5. Praktykum z mikrobiolohiyi: pidruchnyk: [dlya stud.vyshch.navch.zakl.]/ S.P.Hudz, S.O.Hnatush, H.V.Yavorska, I.S.Bilinska, B.M.Borsukevych. – Lviv: LNU iyeni Ivana Franka, 2014. – 436 s. 6. Pyroh T.P. Zahalna mikrobiolohiya: Pidruch. – 2-e vyd., dop. i pererob. – K.: NUKHT, 2010. – 632 s. https://www.studmed.ru/pirog-tp-zagalna-mkrobologya_426401b4f4b.html
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Академічна доброчесність: The policy regarding the academic integrity of the participants of the educational process is formed on the basis of compliance with the principles of academic integrity, taking into account the norms "Regulations on academic integrity at the Lviv Polytechnic National University" (approved by the academic council of the university on June 20, 2017, protocol No. 35).