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Nanotechnology in Medicine and Biology
Major: Biomedical Engineering (Internet of Things)
Code of subject: 6.163.03.E.059
Credits: 5.50
Department: Electronics and Information Technology
Lecturer: Professor Dmytro Zayachuk
Semester: 8 семестр
Mode of study: денна
Завдання: The study of an educational discipline involves the formation of competencies:
General competences:
ZK 1. Ability to apply knowledge in practical situations.
ZK 2. Knowledge and understanding of the subject area and understanding of professional activity.
ZK 5. Ability to conduct research at the appropriate level.
ZK 6. Ability to search, process and analyze information from various sources.
ZK 10. Skills of performing safe activities.
ZK 11. Ability to evaluate and ensure the quality of performed works.
Professional competences:
FC 1. Understand and deeply know the basics and physical principles of modern nanotechnologies as applied to the needs of medicine and biology.
FC 2. Know the possibilities of visualization and observation of nanostructures of biological and medical objects and be able to choose the optimal ones for solving specific tasks.
FC 3. Understand the essence of nanomedicine, its main goals and potential ways to achieve these goals.
FC 4. To have in-depth knowledge of the problem of targeted drug delivery as a medical nanotechnology and treatment method, its purpose, delivery systems and requirements for them, means of addressing systems and their targeting to diseased tissues and organs.
FC 4. To understand and thoroughly navigate the issues of the possibility of using materials of organic origin, in particular, liposomes and dendrimers, for the needs of nanomedicine.
FC 5. Understand and thoroughly navigate the issues of the possibility of using carbon-based materials, in particular, fullerenes and carbon nanotubes, for the needs of nanomedicine.
FC. 6. To understand and thoroughly navigate the issues of the possibility of using metal nanostructures and semiconductor quantum dots for the needs of nanomedicine.
Learning outcomes: Having mastered the discipline, the student must be able to demonstrate the following learning outcomes:
• To understand and deeply know the basics and physical principles of modern nanotechnology in application to the needs of medicine and biology.
• To know the possibilities of visualization and observation of nanostructures of biological and medical objects and be able to choose the optimal ones to solve specific problems.
• To understand the essence of nanomedicine, its main goals and potential ways to achieve these goals.
• To have in-depth knowledge of the problem of targeted drug delivery as a medical nanotechnology and method of treatment, its purpose, delivery systems and requirements for them, means of addressing systems and their guidance on the affected tissues and organs.
• To understand the possibility of using materials of organic origin, in particular, liposomes and dendrimers, for the nanomedicine needs.
• To understand the possibility of using carbon-based materials, in particular, fullerenes and carbon nanotubes, for nanomedicine needs.
• To understand on the possibility of using metal nanostructures and semiconductor quantum dots for the nanomedicine needs.
• To have a substantive notion the application of nanotechnology and nanomaterials in various fields of medicine.
Required prior and related subjects: Pre-requisites: Absent
Co-requisites: Absent
Summary of the subject: The basics of nanotechnology in their application to the needs of medicine and biology are taught: basic concepts of nanomedicine; visualization of nanoobjects of biological origin; targeted drug delivery and system of its implementation; issues of nanocarriers for drug transport, means of their addressing and targeting; modern materials for nanomedicine: liposomes, dendrimers, nanostructures of carbon fullerenes and nanotubes, metal nanoshells and nanoparticles, semiconductor quantum dots; application of nanotechnologies and nanomaterials in various fields of medicine: oncology, cardiology, endocrinology, traumatology, orthopedics, ophthalmology, dentistry; potential risks that the use of nanotechnology in medicine may create.
Опис: Introduction to the course.
Visualization of nano-objects: optical and electron microscopes
Visualization of nano-objects: scanning probe microscopes
Nanomedicine. Address delivery of medicines.
Materials for nanomedicine: liposomes
Materials for nanomedicine: dendrimers
Materials for nanomedicine: fullerenes.
Materials for nanomedicine: carbon nanotubes.
Materials for nanomedicine: metal and metal-containing nanoparticles.
Materials for nanomedicine: quantum dots
Lab on a chip
The latest developments in the field of nanotechnology as applied to biology and medicine
Assessment methods and criteria: Current control: Performances in practical classes, problem solving, test tasks.
Final control: Exam (written and oral components).
Distribution of points on a 100-point scale:
Current control – 32 points
Examination control - 68 points
Of them:
Written component – 60 points
Oral component – 8 points
Критерії оцінювання результатів навчання: The level of assimilation of educational material.
The level of understanding of the educational material.
Current results in lectures and practical classes.
Results of test controls.
Порядок та критерії виставляння балів та оцінок: Excellent (88 - 100 points) - the student completed all the current tasks independently and received a total of 88 - 100% of the maximum possible number of points for the current classes and final control.
Good (71 - 87 points) - the student completed 80% of the current tasks independently and received a total of 71 - 87% of the maximum possible number of points for the current classes and final control.
Satisfactory (50 - 70 points) points - the student completed at least half of the current tasks independently and received a total of 50 - 70% of the maximum possible number of points for the current classes and final control.;
Unsatisfactory (less than 50 points) - the student completed less than half of the current tasks and received less than 50% of the maximum possible number of points for the current classes and final control.
Recommended books: 1. Заячук Д.М., Нанотехнології в медицині та біології, Львів, 2022.
2. Заячук Д.М., Нанотехнології і наноструктури, Львів, 2009.
3. Волков С. В., Ковальчук С. П., Генко В. М., Решетняк О. В.– Нанохімія. Наносистеми. Наноматеріали / К.: Наукова думка, 2008.– 422 с.
4. І.С. Чекман , 3.Р. Ульберг , В.О. Маланчук, Н.О. Горчакова , І. А . Зупанець, Нанонаука, нанобіологія, нанофармація. Монографія - К.:Поліграф плюс , 2012. - 328 с .
5. С. М. Шульга, Ліпосоми і наносоми: структура, властивості, виробництво, Огляд, BIOTECHNOLOGIA ACTA, 2013, V. 6, No 5, с. 19-40.
6. Л.И. Барсуков, Липосомы, Соросовский обозревательный журнал, 1998, №10, с. 2-9.
7. Ю.Д. Семчиков, Дендримеры – новый класс полимеров, Соросовский обозревательный журнал, 1998, №12, с. 45-51.
8. Yu-Chen Wang, Eric Rheaume, Frederic Lesage, and Ashok Kakkar, Synthetic Methodologies to Gold Nanoshells: An Overview, Review, Molecules 2018, 23, 2851; doi:10.3390/molecules23112851
9. Christopher Loo, Alex Lin, Leon Hirsch, Min-Ho Lee, Jennifer Barton, Naomi Halas, JenniferWest, Rebekah Drezek, Nanoshell-Enabled Photonics-Based Imaging and Therapy of Cancer, Technology in Cancer Research & Treatment, 2004, Volume 3, Number 1, pages 33-40.
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