Organic Chemistry

Major: Industrial Pharmacy
Code of subject: 7.226.02.O.007
Credits: 6.00
Department: Organic Chemistry
Lecturer: Budishevska Olha Grygorivna
Semester: 1 семестр
Mode of study: денна
Мета вивчення дисципліни: The purpose of studying the academic discipline and learning outcomes • Study of the basics of the modern theory of the chemical structure of organic substances and its connection with the reactivity and properties of substances. Studying the mechanisms of the reactions of the transformation of organic substances and the peculiarities of the course of the most important reactions. 1. Familiarization with production methods, chemical properties and use of the main classes of organic substances, in particular, those that form the basis of most pharmaceutical preparations. 2. Familiarization with the basic principles of modern classification and nomenclature of organic compounds. Mastery of knowledge about the main classes of organic substances, application of organic substances in the national economy. 3. Study of the general principles of evaluating the chemical properties of organic compounds, which are the basis of the synthesis and analysis of organic substances, in particular, the reactions that are the basis of the pharmacopoeial methods of identification of medicinal substances. 4. Familiarization with safety techniques in the chemical laboratory, with the technique of basic methods of isolation and purification, selected methods of synthesis, studying the properties and establishing the structure of organic substances. 5. Mastery of knowledge about practical aspects of organic chemistry, ways and methods of using its achievements in pharmaceutical and other branches of economy. 6. Mastery of knowledge in the field of structure, production and properties of those classes of compounds that form the basis of most pharmaceutical preparations - such as derivatives of aliphatic and aromatic carbons, heterocyclic compounds, cycloparaffins, carbohydrates, fats, soaps, waxes, peptides and proteins, amino acids, terpenoids, alkaloids, etc.
Завдання: Tasks of the academic discipline in accordance with the educational program The study of an educational discipline involves the formation of competencies in students of education: general competencies: 1. ZK6: Ability to learn and master modern knowledge. 2. ZK 10: Potential for further education. professional competences: 1. Ability to use thorough knowledge of general, inorganic, organic, analytical and physico-colloidal chemistry, chemical and physico-chemical methods of analysis of the composition of substances to the extent necessary for mastering professional disciplines.
Learning outcomes: Learning outcomes according to the educational program As a result of studying the academic discipline, the student must be able to demonstrate the following learning outcomes: 1. Know the basic principles of modern classification and nomenclature of organic compounds. 2. Basics of theories of chemical structure, reactivity and course of chemical reactions of organic compounds 3. To know the main classes of organic synthetic and natural compounds, the peculiarities of their chemical structure and its influence on chemical properties, in particular those used in pharmacy. 4. Know the main methods of obtaining organic compounds, in particular those used in pharmacy or used for the synthesis of medicinal substances. 5. Know the basic methods of isolation, purification and identification of organic compounds. 6. Know the structure and chemical properties of those classes of organic compounds that are studied in further special courses "Methods of Organic Synthesis", "Biological Chemistry and Molecular Biology", "Pharmaceutical Chemistry", "Chemistry and Technology of Medicinal Substances". As a result of studying the academic discipline, the student must be able to demonstrate the following program learning outcomes: PH1 Knowledge of general and inorganic, organic, physical and colloidal, chemical and physico-chemical methods of analysis of the composition of substances in the amount necessary for learning professional disciplines. РН2 Basic knowledge in the field of natural sciences and engineering, necessary for mastering professionally oriented disciplines. PH3 Ability to work with literary sources and information resources. RN4 The ability to communicate, including oral communication and communication in Ukrainian and foreign languages
Required prior and related subjects: Related and the following disciplines: 1. Biological chemistry and molecular biology 2. Pharmaceutical chemistry 3. Chemistry and technology of medicinal substances
Summary of the subject: Abstract of the academic discipline The course "Chemistry 2 (organic chemistry)" is devoted to the study of the basics of the modern theory of the chemical structure of organic substances, the connection of the chemical structure with the reactivity and properties of substances, the study of the mechanisms of the transformation of organic substances and the peculiarities of the course of the most important reactions, the study of the basic principles of the modern classification and nomenclature of organic compounds, as well as production methods, chemical properties and use of the main classes of organic substances, in particular, those that make up the basis of most pharmaceutical preparations.
Опис: The curriculum of the discipline "Chemistry 2 (organic chemistry) is taught to students majoring in 226" Pharmacy, Industrial Pharmacy "field of knowledge 22" Health ". The curriculum defines the purpose and objectives of the discipline, lists the required previous and related and subsequent disciplines, annotation of the discipline, its description, describes methods of knowledge diagnostics and criteria for assessing student learning outcomes, lists of teaching aids and recommended literature, the e-mail address of electronic information resources is given. The course "Chemistry 2 (organic chemistry)" is devoted to the study of the basics of modern theory of chemical structure of organic substances, the relationship of chemical structure with reactivity and properties of substances, the study of mechanisms of conversion of organic substances and the most important reactions, the study of basic principles compounds, as well as methods of production, chemical properties and use of the main classes of organic substances, in particular, those that form the basis of most pharmaceuticals. The curriculum of the discipline "Chemistry 2 (organic chemistry)" contains the following sections: Topic 1. Theoretical foundations of the structure and reactivity of organic compounds. Topic 2. Aliphatic saturated hydrocarbons. Topic 3. Aliphatic unsaturated hydrocarbons. Topic 4. Halogenated aliphatic hydrocarbons. Topic 5. Aliphatic alcohols, ethers, thiols. Topic 6. Aliphatic aldehydes and ketones. Topic 7. Aliphatic carboxylic acids and their derivatives. Topic 8. Aliphatic nitrogen-containing compounds. Topic 9. Organoelement compounds. Topic 10. Compounds with mixed functions. Topic 11. Alicyclic compounds. Topic 12. Aromatic hydrocarbons of benzene series, their halogenated, nitro-, sulfo-derived, amines, nitrogen and diazo compounds. Topic 13. Aromatic oxygen-containing compounds. Topic 14. Multinuclear aromatic compounds. Topic 14. Multinuclear aromatic compounds. Topic 14. The concept of alkaloids. The concept of terpenes, terpenoids, steroids. The concept of nucleic acids.
Assessment methods and criteria: Methods of knowledge diagnostics: 1. Current control: colloquia. 2. Semester control: exam.
Критерії оцінювання результатів навчання: Criteria for assessing student learning outcomes 1 semester (exam) Current control (PC): Colloquium 1 10 points Colloquium 2 10 points Colloquium 3 10 points Colloquium 4 10 points Colloquium 5 10 points Total for PC 50 points Semester control (SC): exam: Written component 40 points Oral component 10 points Total for SC 50 points Total for the discipline 100 points Procedure and criteria for scoring and evaluation: On a 100-point scale of the University and on a national scale: 88-100 points "excellent"; 87-71 points - "good"; 70-50 points - "satisfactory"; 26-49 points - "unsatisfactory"; 0-25 points - "Not certified".
Порядок та критерії виставляння балів та оцінок: 100–88 points – (“excellent”) is awarded for a high level of knowledge (some inaccuracies are allowed) of the educational material of the component contained in the main and additional recommended literary sources, the ability to analyze the phenomena being studied in their interrelationship and development, clearly, succinctly, logically, consistently answer the questions, the ability to apply theoretical principles when solving practical problems; 87–71 points – (“good”) is awarded for a generally correct understanding of the educational material of the component, including calculations, reasoned answers to the questions, which, however, contain certain (insignificant) shortcomings, for the ability to apply theoretical principles when solving practical tasks; 70 – 50 points – (“satisfactory”) awarded for weak knowledge of the component’s educational material, inaccurate or poorly reasoned answers, with a violation of the sequence of presentation, for weak application of theoretical principles when solving practical problems; 49-26 points - ("not certified" with the possibility of retaking the semester control) is awarded for ignorance of a significant part of the educational material of the component, significant errors in answering questions, inability to apply theoretical principles when solving practical problems; 25-00 points - ("unsatisfactory" with mandatory re-study) is awarded for ignorance of a significant part of the educational material of the component, significant errors in answering questions, inability to navigate when solving practical problems, ignorance of the main fundamental provisions.
Recommended books: Educational and methodical support 1. Yu.O.Lastukhin, S.A.Voronov. Organic chemistry. Kind. "Center of Europe". 2004 2. Budishevska O.G. Electronic educational and methodical complex used to ensure the discipline "Chemistry 2 (organic chemistry)" for students majoring in 226 "Pharmacy, industrial pharmacy" (https://vns.lpnu.ua/course/view.php?id=12310 ) 3. SA Voronov, VA Donchak, AM Kohut Organic Chemistry. Lviv Polytechnic National University Publishing House.-2021.- 486 p. 4. Donchak V.A., Panchenko Y.V., Voronov S.A. Purification of substances by steam distillation, fractional and vacuum distillation // Methodical instructions. Lviv: Lviv Polytechnic National University Publishing House. 2007 5. Panchenko Y.V., Vasiliev V.P., Voronov S.A. Qualitative elemental analysis and determination of the most important constants of organic substances // Methodical instructions. Lviv: Lviv Polytechnic National University Publishing House. 2007 6. Panchenko Y.V., Vasiliev V.P., Tokarev V.S. Obtaining and studying the properties of saturated, unsaturated and aromatic hydrocarbons // Methodical instructions. Lviv: Lviv Polytechnic National University Publishing House. 2006 7. Voronov S.A., Budishevskaya O.G. Aliphatic oxygen-containing compounds // Methodical instructions. Lviv: Lviv Polytechnic National University Publishing House. 2004. 8. Voronov S.A., Budishevskaya O.G. Compounds with mixed functions. Hydroxy acids, carbohydrates // Methodical instructions. Lviv: Lviv Polytechnic National University Publishing House. 2005. 9. Voronov S.A., Budishevskaya O.G. Amino acids. Proteins // Methodical instructions. Lviv: Lviv Polytechnic National University Publishing House. 2005. 10. Voronov S.A., Budishevskaya O.G. Aromatic hydrocarbons and their halogenated, nitro-, sulfo-derived // Methodical instructions. Lviv: Lviv Polytechnic National University Publishing House. 2005. 11. Voronov S.A., Budishevskaya O.G. Aromatic oxygen-containing compounds // Methodical instructions. Lviv: Lviv Polytechnic National University Publishing House. 2005. 12. Voronov S.A., Budishevskaya O.G. Heterocyclic compounds // Methodical instructions. Lviv: Lviv Polytechnic National University Publishing House. 2005. 13. Glubish P.A. Organic synthesis. Part 1 and 2.-K., 1997. 14. Litkovets O.K., Nosan V.M., Klim M.I. Stereochemistry of organic compounds.-Lviv, DULP. 1996. 15. Litkovets O.K., Pokhmurskaya M.V. Polymer compounds. DULP. 1996. 16. L.A. Kazitsyna, N.B. Kupletskaya Application of UV, IR and NMR spectroscopy in organic chemistry.-M: Ed. "Higher School" .- 1971.- 264 p. Recommended Books Basic: 17. Dombrovsky V.I., Naidan V.M. Organic chemistry.-K .; Higher education, 1992. 18. Neyland O.E. Organic chemistry.- M .: "Higher school" .- 1990. 19. Terney A. Modern organic chemistry (in two books). Per. с англ., - М .: Мир. 1981 20. Morrison R., Boyd R. Organic Chemistry. -M .: Peace. 1974. 21. Sykes P. Mechanisms of organic reactions. -M .: Chemistry. 1991 22. Puchin V.O., Litkovets O.K., Nosan V.M. etc. Individual syntheses from a laboratory workshop on organic chemistry. DULP. 1980. 23. Puchin V.O., Litkovets O.K., Fedorova V.O. etc. Organic synthesis.-Lviv, LPI. 1977. 24. Litkovets O.K., Nosan V.M., Klim M.I. Functional chemical and spectral analysis of organic compounds.-Lviv, LPI. 1987 25. Voronov SA, Lastukhin YO Synthesis of carbochain polymers.-Lviv. LPI. 1989. Auxiliary: • Chernykh V.P., Zimenkovsky B.S., Gritsenko I.S. Organic chemistry (in three books) .- Kharkiv, "Osnova". 1996. • Litkovets O.K., Pokhmurska M.V. Polymer compounds. DULP. 1996. • Organic. Workshop on organic chemistry. In 2 volumes.-M .: 1992. Information resources: Electronic educational and methodical complex used to ensure the discipline "Chemistry 2 (organic chemistry)" for students majoring in 226 "Pharmacy, industrial pharmacy"- 2021 -at the link https://vns.lpnu.ua/course/view.php?id=12310 .
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