Home/ Majors directory/Biotechnology and Bioengineering/Biotechnology of Proteins
Biotechnology of Proteins
Major: Biotechnology and Bioengineering
Code of subject: 6.162.02.E.067
Credits: 3.00
Department: Technology of Biologically Active Substances, Pharmacy and Biotechnology
Lecturer: Associate Professor, Ph.D. Zoriana Hubrii
Semester: 7 семестр
Mode of study: денна
Завдання: The study of an educational discipline involves the formation of competencies in students of education:
INT The ability to solve complex specialized tasks and practical problems characterized by complexity and uncertainty in biotechnology and bioengineering, or in the learning process that involves the application of theories and methods of biotechnology and bioengineering
general competences:
GC1. Ability to apply knowledge in practical situations
GC5. Ability to learn and master modern knowledge
professional competences:
PC2. The ability to work with biological agents in biotechnological processes (cells of microorganisms, fungi, plants, animals; viruses; cell components; enzymes, immobilized cells and enzymes), to determine their morphology and physiological features.
PCS1.7. Ability to apply knowledge of biotechnological processes of production of pharmaceuticals, diagnostic bioproducts and technological modes of biosynthesis, biotransformation, processing of biomass for its production.
Learning outcomes: PR14. Be able to justify the choice of a biological agent, the composition of the nutrient medium and the method of cultivation, the necessary auxiliary works and the main stages of the technological process, methods and methods of cultivation, biosynthesis, biotransformation, bioindication and biotesting of biological objects.
PR29. Identify and perform validation work necessary to confirm the control of critical aspects of specific technological operations in biopharmaceutical production.
A&R2. The ability to realize the need for lifelong learning in order to deepen the acquired and acquire new professional knowledge.
A&R3. The ability to take responsibility for the work performed, to make decisions independently, to achieve the set goal in compliance with the requirements of professional ethics.
COM2. The ability to use various methods, including modern information technologies, for effective communication at the professional and social levels.
Required prior and related subjects: Previous academic disciplines:
Biology;
General microbiology and virology;
General biotechnology;
Pharmaceutical chemistry.
Associated and following academic disciplines:
Bioengineering (cellular, genetic);
Biotechnology of fermentation.
Summary of the subject: Raw material for obtaining of industrial biologically active compounds and protein drugs. Typical technological scheme of synthesis of microbial feed protein. Specifics of growing feed yeast depending on the type of raw material. Microorganisms-producers, conditions of cultivation, technological options and specifics. Biotechnology of fungal protein. Specifics of cultivation of fungal cultures - producers of the protein, the advantages of fungal protein. Biotechnology of obtaining aminoacids by microbiological method. Obtaining of L-lysine, L-glutamic acid, L-tryptophan, separation, purification, drugs based on them.
Опис: Raw material for obtaining of industrial biologically active compounds and protein drugs. Typical technological scheme of synthesis of microbial feed protein. Specifics of growing feed yeast depending on the type of raw material. Microorganisms-producers, conditions of cultivation, technological options and specifics. Biotechnology of fungal protein. Specifics of cultivation of fungal cultures - producers of the protein, the advantages of fungal protein. Biotechnology of obtaining aminoacids by microbiological method. Obtaining of L-lysine, L-glutamic acid, L-tryptophan, separation, purification, drugs based on them.
Assessment methods and criteria: The following types of control are used: current and semester. Current control is a control that is carried out during the study of an educational discipline in order to identify the degree of understanding of the student's learned educational material and the ability to apply it in practical work. Current control is carried out in laboratory classes. The obtained results of current control are used by the teacher to adjust the methods and means of teaching students, organize their independent work, and during the semester control and assessment of students' knowledge. Forms of ongoing control: individual survey upon admission to laboratory work, evaluation of laboratory work, protection of laboratory work.
Semester control is a type of final control that reveals the student's level of mastery of the academic discipline, taking into account the results of the current control. Examination form: written (test) with a mandatory oral component.
Критерії оцінювання результатів навчання: Current control - 30 points:
Laboratory works - 20 points;
Homework - 10 points.
Examination control - 70 points:
written component - 60 points;
oral component - 10 points.
Порядок та критерії виставляння балів та оцінок: 00–88 points – (“excellent”) is awarded for a high level of knowledge (some inaccuracies are allowed) of the educational material of the component contained in the main and additional recommended literary sources, the ability to analyze the phenomena being studied in their interrelationship and development, clearly, succinctly, logically, consistently answer the questions, the ability to apply theoretical provisions when solving practical problems;
87–71 points – (“good”) is awarded for a generally correct understanding of the educational material of the component, including calculations, and reasoned answers to the questions posed, which, however, contain certain (insignificant) shortcomings, for the ability to apply theoretical provisions when solving practical tasks;
70 – 50 points – (“satisfactory”) awarded for weak knowledge of the component’s educational material, inaccurate or poorly reasoned answers, a violation of the sequence of presentation, or weak application of theoretical provisions when solving practical problems; 49-26 points - ("not certified" with the possibility of retaking the semester control) is awarded for ignorance of a significant part of the educational material of the component, significant errors in answering questions, inability to apply theoretical provisions when solving practical problems;
25-00 points - ("unsatisfactory" with mandatory re-study) are awarded for ignorance of a significant part of the educational material of the component, significant errors in answering questions, inability to navigate when solving practical problems, and ignorance of the main fundamental provisions.
Recommended books: 1. Фармацевтична біотехнологія: Біотехнології виробництва готових лікарських форм: навч. посібн. / Ю. М. Краснопольський, Д. М. Пилипенко. – Харків: ТОВ «Друкарня мадрид», 2020. – 279 с.
2. Фармацевтическая биотехнология: Аспекты фармацевтической химии: учеб. пособие / Ю.М.Краснопольский, О. В. Звягинцева. – Харьков : НТУ «ХПИ», 2018. – 248 с.
3. Актуальные проблемы биотехнологии и биоинженерии / под ред. А. Н. Огурцова. – Харьков : «Типография Мадрид», 2019. – 240 с.
4. Фармацевтичні та медико-біологічні аспекти ліків. Навчальний посібник / За ред. І.М.Перцева . - Видання друге. – Вінниця: НОВА КНИГА, 2007. – 728 с.
5. Буценко Л.М., Пенчук Ю.М., Пирог Т.П. Технології мікробного синтезу лікарських засобів. - К.: НУХТ, 2010. — 323 с.
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