Toxicological Chemistry

Major: Pharmacy, Industrial Pharmacy
Code of subject: 6.226.00.O.023
Credits: 4.00
Department: Technology of Biologically Active Substances, Pharmacy and Biotechnology
Lecturer: associate Professor, Ph.D. Kurka Mariya Severynivna
Semester: 4 семестр
Mode of study: денна
Learning outcomes: • basic knowledge of toxicological examination of organic and inorganic substances and biological material; • conduct toxicological analysis of selected research objects; • be able to summarize and systematize information about various toxic substances and their negative impact on the human body; • ability to realize the need for lifelong learning in order to deepen the acquired and acquire new professional knowledge.
Required prior and related subjects: Prerequisites: Chemistry 1 (General and Inorganic Chemistry) Chemistry 2 (Organic Chemistry) Physical and colloid chemistry Chemical methods of analysis of the composition of substances Physics Biology and physiology with the basics of anatomy Co-requisites: Biological chemistry and molecular biology Pharmacy technology of drugs Pharmacognosy Pharmaceutical chemistry Pharmacology
Summary of the subject: The milestones of toxicological chemistry in Ukraine. Poisoning and its classification. Detoxification. Methods of analysis used in toxicological chemistry. Toxic and potent substances which are isolated from biological material by the process of steam distillation; the separation of one chlorine derivatives from others; allocation of alkaloids; substances that are isolated from biological material by the process of objects mineralization; detection of metallic poisons.
Assessment methods and criteria: • written reports from laboratory work, oral questioning, final test –40 points; • final control (exam) – 60 points (written-oral form).
Recommended books: 1. Токсикологічна хімія / В.П. Крамаренко. – К.: Вища школа, 1995. – 424 с. 2. Общая токсикология / под ред. Б.А. Курляндского. - М.: Медицина, 2002. – 614 с. 3. Книга про отрути та отруєння: Нариси токсикології / Пер. з рос. Трахтенберг І.М. – Тернопіль, 2008. - 364с. 4. Токсикологія продуктів харчування / С.А. Воронов, Ю.Б. Стецишин, Ю.В. Панченко, А.М. Когут. – Львів: Видавництво Львівської політехніки, 2014. – 556 с. 5. Судова медицина / Підручник за редакцією Б.В.Михайличенка. – К. ВСВ «Медицина», 2017. – 448 с.