Pharmacokinetics

Major: Pharmacy, Industrial Pharmacy
Code of subject: 6.226.01.E.080
Credits: 3.00
Department: Technology of Biologically Active Substances, Pharmacy and Biotechnology
Lecturer: Assoc. Prof., Ph.D. Krychkovska Aelita
Semester: 5 семестр
Mode of study: денна
Learning outcomes: • know the terms and laws pharmacokinetics of medicines (drugs); • know the pharmacokinetics regarding specific groups of medicines and the most important practical medicine products; • be able to use the knowledge of general and applied to predict the pharmacokinetic behavior of drugs relative living organism depending on their chemical nature, prevention of adverse effects of drugs and their more effective use, as well as for the creation, research and introduction of new health of pharmacologically active compounds and developing industrial production technologies
Required prior and related subjects: Prerequisites: • General and Inorganic Chemistry. • Organic Chemistry. • Biology and Physiology with the basics of anatomy. Co-requisites: • Pharmacology. • Pharmacotherapy. • Clinical Pharmacy
Summary of the subject: General pharmacokinetics. Basic concepts, terms and the estimated value of pharmacokinetics. Ways of introducing drugs. Absorption. The distribution of drugs in the body. Biological barriers. Deposit. Chemical transformation (metabolism) of drugs in the body. By removing drugs from the body. Dependence pharmacokinetics of drugs on their properties and usage. Applied pharmacokinetics. The pharmacokinetics of drugs that regulate the function of the peripheral and central nervous system. The pharmacokinetics of drugs that regulate the functions of the executive organs and systems. Pharmacokinetics of antimicrobial, antiparasitic and protyblastomnyh drugs. Pharmacokinetics of drugs used in malignant tumors.
Assessment methods and criteria: • Writing reports practical work, individual task, oral examination, test control work (40 points) • Final control (60 points control measure, test), written-oral form (60 points).
Recommended books: 1. Чекман А.Д. Довідник з клінічної фармакології та фармакотерапії.-К., Медицина, 2004. 2. Скакун М.П., Посохова К.А. Фармакологія. – м. Тернопіль, Укрмедкнига, 2003. 3. Болібрух Л.Д., Кричковська А.М., Марінцова Н.Г. та ін. Основи фармакології. – м. Львів, Тріада плюс, 2010. 4. Загальна фармакокінетика./ За ред. акад. Б.А. Самури. – Тернопіль: ТДМУ, 2009. – 356 с.