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General Immunology
Major: Biotechnology and Bioengineering
Code of subject: 6.162.01.E.063
Credits: 3.50
Department: Technology of Biologically Active Substances, Pharmacy and Biotechnology
Lecturer: Associate Professor, Ph.D. Olena Fedorova
Semester: 8 семестр
Mode of study: денна
Завдання: Ability to conduct research at an appropriate level.
Ability to work in an international context.
. Ability to show initiative and entrepreneurship
Learning outcomes: to know the theoretical foundations of molecular mechanisms of immunity formation;
– to know a modern biotechnology of vaccines producing;
– to understand a receptor signaling, enzymatically regulating and genetic determining mechanisms of the immune response formation
The ability to determine bioprocesses and producers for the creation of pharmaceutical, diagnostic, immunological, prophylactic biological preparations and to cause changes in the structure of the hereditary apparatus and the functional activity of bioagents.
To be able to isolate from natural substrates and identify microorganisms of different systematic groups. To determine the morphological-cultural and physiological-biochemical properties of various biological agents
To be able to conduct experimental studies with the aim of determining the influence of physico-chemical and biological factors of the external environment on the vital activity of the cells of living organisms.
To have control methods of biological objects, the quality of raw materials and finished biotechnological products and to carry out qualitative and quantitative analysis of substances of inorganic, organic and biological origin
The ability to use a variety of methods, including modern information technologies, for effective communication at the professional and social levels
Required prior and related subjects: Prerequisites:
Microbiology,
General biotechnology
Co-requisites:
Genetics (general and molecular)
Summary of the subject: Two major types of immune response. Cells responsible for immunity. B-lymphocytes. T-lymphocytes. Morphology of immune system. The concept of phagocytosis. Complement system. Interferons. Antigens. Antibodies. Antigen-antibody reaction. Monoclonal antibodies. Allergic reactions. Vaccines. Diseases of an immune system. Methods of immunodeficiencies correction.
Опис: Chapter 1. Subject, tasks, basic concepts.
Chapter 2. Morphology of the lymphatic system.
Chapter 3. Congenital protective factors
Chapter 4. Acquired immunity.
Section 5. Transplantation immunity
Section 6. Vaccines
Consideration of the methods and techniques of the laboratory workshop for the analysis of biotechnology and the approbation of the technique of performing some laboratory studies of specific bioproducts, biopreparations and biotests for various purposes in the field of bioindustry, in particular in pharmaceutical biotechnology
Section 7. Peripheral departments of the immune system
Section 8. Other forms of immune response
Chapter 9. Autoimmune diseases
Section 10. Monoclonal antibodies
Section 11. Complement system.
Chapter 12 Diseases of the immune system.
Assessment methods and criteria: written reports from laboratory work, individual work –30 points;
• final control (test) – 70 points (written-oral form).
Критерії оцінювання результатів навчання: Written and oral control - 70 points
Report on laboratory work - 18 points
Completion of the control work - 12 points
Порядок та критерії виставляння балів та оцінок: The main methods of knowledge diagnosis are: current (PC) and semester control (SC), which is carried out from educational material, the scope of which is determined by the work program of the discipline for the semester.
Current control is carried out during lectures and laboratory classes in order to check the level of assimilation of theoretical and practical knowledge and skills of the student. PC is conducted in the form of: performance of control work, written and oral control and protection of laboratory work.
Semester control is carried out in the form of differentiated credit (credit). Differentiated credit is a form of SC of the student's study results exclusively for all types of work provided by the program of the academic discipline.
Recommended books: A set of electronic methodical support of the educational discipline "General immunology" in the National Academy of Sciences of the National University "Lviv Polytechnic" [Electronic resource].-Access mode: https://vns.lpnu.ua/course/view.php?id=14954
2. Methodical recommendations and materials for organizing students' independent work.
3. Synopsis of key lectures.
4. Demonstration material in the form of diagrams, drawings, photomicrographs, photographs, microfilms presented using computer technology.
5. Variants of tasks for students' independent work - a list of multimedia presentation topics.
1. Medical microbiology, virology and immunology. — 3rd ed., updated. and added // Shirobokov V. P. under the editorship) – Vinnytsia, New Book, 2021. – 920 p.
2. Medical microbiology. Handbook of Microbial Infections: Pathogenesis, Immunity, Laboratory Diagnosis, and Control: 19th Edition: In 2 Volumes. Volume 2 / Michael R. Barer, Will Irving, Andrew Swann, Nelyun Perera/ translated by Serhiy Klymniuk and others. - All-Ukrainian Specialized Publishing House: Medicine, 2021. – 384p.
3. Fundamentals of immunology (theory and practice: study guide / M. S. Tvorko, S. I. Klymnyuk, N. I. Tkachuk. - Ternopil: Ukrmedknyga, 2009. - 298 p.
4. Immunology: lectures for students of the medical faculty / M.S. Creatively -. Ternopil: TDMU, 1998. - 186 p.
5. Roit A. Fundamentals of immunology./ Translation. All-Ukrainian specialized publishing house: Medicine,.-2001.
6. Yakobysiak M. Immunology. /- Vinnytsia.: New book.-2004.
Уніфікований додаток: Lviv Polytechnic National University ensures the realization of the right of persons with disabilities to obtain higher education. Inclusive educational services are provided by the Service of accessibility to learning opportunities "Without restrictions", the purpose of which is to provide permanent individual support for the educational process of students with disabilities and chronic diseases. An important tool for the implementation of the inclusive educational policy at the University is the Program for improving the qualifications of scientific and pedagogical workers and educational and support staff in the field of social inclusion and inclusive education. Contact at:
St. Karpinsky, 2/4, 1st floor, room 112
E-mail: nolimits@lpnu.ua
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