Pharmaceutical Chemistry

Major: Biotechnology and Bioengineering
Code of subject: 6.162.01.E.083
Credits: 4.00
Department: Technology of Biologically Active Substances, Pharmacy and Biotechnology
Lecturer: Associate Professor, Ph.D. Bolibrukh Lilia Dmytrivna
Semester: 5 семестр
Mode of study: денна
Learning outcomes: As a result of study of discipline a student must be able to demonstrate the following learning outcomes: • to be able to use fundamental knowledge of general, inorganic, analytical, physical and colloid chemistry in the extent necessary for mastering general engineering and professionally oriented subjects; • tobe able to analyze raw materials, intermediates, target productsof biotechnological production,bioproducts, biopreparations; • to know the basics of implementing chemistry of natural, pharmaceutical, toxemiacarcinogenic and other biologically active substances, structure and properties of inorganic, organic and bioorganic compounds, and also methods of their qualitative and quantitative analysis in the biotech and pharmaceutical industries.
Required prior and related subjects: Prerequisites: • General Chemistry • Organic chemistry • Analytical Chemistry Co-requisites: • Chemistryof biological active substances • Chemistry of carcinogens
Summary of the subject: Inorganic medicines. Supplements of halogens, iodine, halides. Supplements of hydrogenperoxide.Supplements of boron, magnesium, calcium and barium compounds. Methods of identification and quantitative determination. Organic medicines. Aliphatic compounds. Alcohols and their esters. Aldehydes and their derivatives. Hydroaromatic compounds. Reactions of identification and quantification methods, storage andusage. Aromatic compounds. Phenols. Derivatives of aromatic acids. Derivatives of amides of sulfanilic acid. Heterocyclic compounds. Derivatives of furan, pyrazole, pyridine, pyrimidine, phenothiazine.
Assessment methods and criteria: • written reports from laboratory work, test, control work - 50 points; • final control - 50 points (control, exam): written-oral form.
Recommended books: 1. М.М.Туркевич. Фармацевтическая химия. К., Вища школа. 1973. -495 с. 2. М.Д.Машковский. Лекарственные средства.т.1;2, Харьков. “Торсинг”. 1998. -543, 590. 3. За заг. редакцією проф. Безуглого П.О. Фармацевтична хімія. Харків «Золоті сторінки». 2002. -447с.